KMID : 0644120090220030025
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Journal of Oriental Gynecology 2009 Volume.22 No. 3 p.25 ~ p.35
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Effects of Boheo-tang and Boheo-tang plus Cervi Pantotrichum Cornu : on Immune Response in Postpartum mice
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Lee Eun-Hee
Kim Tae-Hee
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Abstract
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Purpose: The purpose of this study is to investigate the effect of Boheo-tang (B) and Boheo-tang plus cervi pantotrichum cornu (B+CP) on immune response in postpartum C57BL/6N mice.
Methods: Normal saline(control), B and B+CP (8/g) were administerd p.o. twice a day for 20 days. Subpopulation of T and B lymphocyte were accessed by flow cytometric analysis.
Results: Splenic T and B lymphocytes were increased by the treatment of B. Subpopulation of cytotoxic T lymphocytes in the spleen, were significantly increased by both treatment of B and B+CP. Subpopulation of cytotoxic T lymphcytes in the thymus, were significantly increased by both treatment of B and B+CP. IL-4 production was significantly increased by the treatment of B+CP.
Conclusion: This study shows that treatment of Boheo-tang and Boheo-tang plus cervi pantotrichum cornu can improve postpartum immune response in C57BL/6N mice.
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KEYWORD
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Boheo-tang, Cervi Pantotrichum Cornu, Immune response, postpartumb mice
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